kinda depends on the volume you're shooting...
changing a progressive press from one caliber to the next can be quite a mission. you could always buy another turret and keep the dies for a particular caliber set up in their own turret, but you may end up having to swop shell plates etc. amount of work and complexity depends on the press.
progressive presses really shine when it comes to straight wall pistol cases. for rifle, I tend to do too many (rifle) brass prep steps to make it feasible.
progressive presses are also fairly complex machines and quality makes a massive difference. if you compare single stage presses, IMHO there is not that much difference between a Lee Cast press and RCBS etc. but if you compare a Lee Pro 1000 to a Dillon it is night and day.
when it comes to high accuracy long range ammo, I doubt if you would get consistent enough powder throws from a progressive, mostly done off the press with a trickler and high quality scales.
hope that helps
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