As the ADI guide shows, 2208 is really a bit slow for the 204. I would recommend Viht N133. I'm using it in my 20 Tactical, getting 3,900fps+ with 40gr vmax. The 20 Tac case is smaller than the 204 Ruger too...
45-46gr in the 308 with 150gr projectiles should be a good safe load in the 308
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