I’ve done a lot of load dev for a heap of different rifles and calibres over the years. Yet to find one where the accuracy node and POI is much different with or with out suppressor. One point I have noticed is that you increase the rate or amount of carbon fouling with suppressor. Hence I do nearly all load dev with out suppressor and then fine tune load and POI with suppressor. Most of my suppressors are DPT, you may see something different with other brands, especially the heavier ones.
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