I'm with you ChrisW have always cleaned the bore after use, it doesn't matter if it's one shot or 20 still clean with solvent etc. Can't say I have noticed huge differences in point of impact changes not enough to miss an animal, anyway.
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On hunting rifles I quite often just use a pull through on them after light use to clean out any powder residue and light carbon and sometimes patch through some oil before they go back in the safe.
I find with my other target/LR rifles first round shoot a bit lower depending on rifle but I would say 1/2moa on my main one