From all my reading @
veitnamcam, no. The offending prions are extremely heat resistant. You would have to turn the brain into cinder before it would be effected.
This is in contrast to like of tuberculosis. Cooking tuberculosis infected meat makes it safe to eat. The danger is getting the disease into your lungs through the blood or as been suggested even the vapour that can come off the gut when you are gutting it....but I digress.
On that point though, even though I eat offal I always inspect it well before I choose to take it as food. Slightest little thing that even give a hint of and abnormality I throw it.....usually into the maggot farm for the chooks.
Cheers
Phil