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So what loads are you working on?, my pet loads so far:
-120 TTSX at 3450
-160 Accubond at 3050
-180 Berger VLD at3050

Will likely use the TTSX and the VLD as a working pair as they shoot to...

It is normal when you switch primers for stuff to change, load a few with Rem 9 1/2 mag primers and see what happens, if you load test on a bipod/rear bag and use a benchrest type techinque shooting,...