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Each 4 shot test is only 1/2 grain up to he will still get a ladder. One other suggestion is that sandbags are used for consistent support both front and rear in order to minimise shooter error.

With 16 thou" yr probably safe and may get lower pressures. Bullet type, case type, primers and powder batch lot as well as the characteristics of your rifle can all affect the outcome though. As the...

If you havent jammed the bullet into the rifleling it is likely you will have lower pressure and velocity. BUT; if you have jammed you could get high or even very dangerous pressures.

You will get a better picture of differences shot to shot.

Yes to a minute cooling between shots.
Chrony is helpful but not essential initially.
Recorde each shot poi with its matching load data.
Do not adjust sights between shots.
Better at 200 than...