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See, this is exactly the sort of approach that I think bring success with the 222/223; being disciplined and sure of yourself and your gear. I think too many people just look at calibres themselves...

I had a big Billy goat take off after my mate shot him through the front shoulder with a 7mm08 from around 30m, later found the bullet had gone from front right shoulder diagonally through and lodged...

My experience is limited, but I think a good shot with a 223 or similar will do the job on deer etc. I'm not good enough to bank on calibres like that so I'm quite happy to use something full power...