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Chris I think you're overcomplicating things (and I think your calculations are a little off). Stick with zeroing for 200m, then you can take anything from 0 out to a good 300, possibly 400 without...

A lot of calibers are much of a muchness. I don't know much about the 25-06 admittedly, but that's an awful big case to fill with less powder than a 7mm-08 takes.

You put it in the same category...