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I'd have to disagree Hamish, 243 can easily smack targets at 500. Just because you can take an animal at 500 doesn't mean you should. 243 is a great calibre but long range hunting cartridge it is not.

Go 7mmRM and be done with it. Covers all bases from 0 - 500 with ease, recoils not bad plenty of options to address that if need be. Factory ammo available in pretty much every hunting shop and if...