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That is for quite a long CoL. I think you will be limited to 2.820" in the Kimber, maybe a little less, in which case I wouldn't jump in at 41gr. Shorter CoL will crank up the peak pressure. Try...

I think so. Work up to 39gr of your 2208. Might get there with 38gr.

With a 14" barrel you'll be limited to a little over 2400 ft/sec with a 150gr bullet and AR2208 anyway. I'm not sure that changing either the bullet, powder, or quantity of powder is such a good...