What caliber are you running them in? Given the 180 gn I assume 300WM or WSM ? As others have stated they are a bonded construction so need to be drive hard and do their best work with terminal velocities >2200 fps, some might argue 2400. I have run in 7mm 150gn in magnums with good results so long as you don’t push the range too far. As @wsm junkie stated hitting bone is helpful
Bookmarks