Nick Harveys 1980 manual has the two cartridges listed and it looks as if the loads are broadly similar. The .250-303 has a bit more capacity and works at lower pressure. There is a note saying to reduce all charges by 10% for Lee Enfields. This would mean that max charges would be below the .250-3000. Any particular powder you are interested in? I would be ultra careful with any of his loads as most were never pressure tested and copied from other un named scources.
GPM.
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