Two ladders with similar results, 4 adjacent charge weights touching in that first ladder pictured, supported by the second ladder, then it all flies apart very badly with 2x three-shot groups at the centre charge weight and at the same seating depth. It has to be something else that has changed between the two outings, and changed very quickly rather than progressively. Obvious stuff first - I'd be back to shooting off my own bags for starters. I'd also be inclined to then stick with c.43gr (at whatever jump the ladder testing was at) until the problem is IDed before chasing further refinement.
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