Personally I would just go standard 22-250 with a 1-8 twist. I had Truflite rebarrel a kimber of mine in standard 22-250 with 1-8 twist a while back. I was tempted at the time by the sirens song of other less available/newer cases. However, I am really glad I went standard 22-250. It shoots my reloads with the 80grain eldm very well and I can still go buy factory fodder in a pinch. I got the 1-8 twist so I wouldn't risk shucking jackets with the 50-55 grain factory fodder. My 1-8 doesn't seem to stabilize the 88grain eldm very well so if you wanted to shoot those you would probably want a 1-7.
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