Q: What happens when your case has lots of room left?
A: Nothing.
But it is considered poor practice, even though no manufacturer, despite trying, has managed to replicate the "secondary explosive effect" or "flashover" or "detonation"
This is a myth that has been perpetuated for a long, long, long time.
Using bulkier/slower powder is good advice. alternatively top up the case with corn meal or dacron.
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