I've used both a .22-250 and a .223 a fair amount on fallow and a little on reds. Shot two fallow with 50gr z/v max first one was a neck shot and she fell over straight away. Second one didn't go as well, was a yearling spiker and I aimed at the neck again. He appeared to stumble at the shot however ran of with the rest of the mob. Searching revealed no sign of a hit or deer. About 6 weeks later I shot a yearling spiker in the same place, this time with a 55gr soft point in the chest. When I boned him out there was some bruising/ wounding on its neck, can't be sure it's the same animal but was enough to make me avoid the varmint projectiles for deer.
.223 will work fine just have to realise its limits better than I did that day.
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