In my experience the grendel is not a replacement for the 223. They are quite different. I have found that the 6.5g on small critters makes a lot of mess. It also has quite a lot of drop ado not as good for varmints.
I would drop the 22hornet and the 243. The 06 is your range gun. The 55 is you red stag gun. The grendel is your fun gun that can do a bit of everything.
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