The response time in a bigger card can be slightly longer, especially when the card starts filling up. But the difference between .7 of a second and 1.2 seconds to arm the cam could mean missing out on seeing the beasts head and getting a pretty picture of it's arse instead.
The side facing triggers on my cams help with that because they arm the cam before the animal gets to the camera trigger sensor but on some it could be a slight problem.
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