I've got the same deal shooting different projectiles out of the same rifle.
I zero for the load i use often, and for other loads that require a different zero I record the Adjustments relative to that.
My 223 for example, is zeroed at 150 yards for 40gn vmax.
to zero for Hornady 53gn at 150yds, I recorded in my little black book I have to move the dials 4 clicks up and 4 left.
Seems to work.
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