Using two pure breeds to cross and produce a utility animal will produce an animal that is superior to the mean line of the two parent breeds. The offspring will be consistent and predictable.
Problems will only arise when the cross-bred is bred with IF it is bred to another similar cross-bred or to one of the parent breeds. In either case the hybrid vigour of the first cross is lost and the genetic mix is randomised with a lot of variation across the offspring. Remember Gregor Mendel's sweet peas that we all learnt about in High School Bio.
If a cross-bred is to be bred from it should be crossed to a third unrelated breed. This will maintain the vigour and consistency.
Genetic progress in breeding is best achieved by selection within a pure breed, but in the case of dogs, because the breeds carry such a high 'inbreeding coefficient' ( this is a mathematical ratio of close breeding relationship) from memory around 60% crossing is a good option to breed a utility dog.
For example Greyhounds ( which are anatomically perfect and carry no genetic faults ) cross very well with Border Collies to produce Lurchers. Such a dog could be crossed to a Staffy to produce awesome pigdogs for example.
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