If primarily goats then get a 223. As said, plenty of affordable ammo and you will learn to shoot well without hammering yourself as you would with a heavy caliber. I've shot hundreds of goats and this is my choice and where I cull there are a few deer around for the pot as well, never had an issue because of the confidence you build with the easy to shoot 223.
If only a choice of the two mentioned then 243.
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