I used to sight my 44 with subs dead on at 100, but this resulted in misses over the top on closer shots. Zero at 65 and it is easier to allow a little hold over at 110.
As has already been stated, the trajectory will be the same as your 22. To explain, if different bullets all start off at the same speed then the flight time to the target is the same, which means the time that gravity has to act on the projectiles is the same
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