Always sight it in & test loads in the same configuration you will shoot with.
Do not sight it in without suppressor then expect it to shoot to the same point of impact or group the same with that particular ammo after its suppressed, as the suppressor will alter the barrel harmonics.
By all means go out, shoot it, and have some fun if you are wanting to shoot it - just expect to have to adjust zero etc again after its suppressed. No big deal.
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